Proliferation assays. Primary structure of the gene for the murine Ia antigen-associated invariant chains Ii : an alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin. Please note: You are asking volunteers to find and take a photo of the headstone. Ii p41 contains an additional exon, 6b, which encodes a 64—amino acid sequence that is located in the lumenal Ii domain 9. Thanks for your help! Include my email in message to volunteers. Antigen presentation enhanced by the alternatively spliced invariant chain gene product p View Flower. T-lymphocyte entry into the central nervous system.
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Member Sign In. Cell culture supernatants were collected at hour incubation for cytokine analysis. Address correspondence to: Scott S. Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II restricted T cells.
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In this situation, endocytic processing may not be required for initial CNS Ag presentation. Failed to delete photo. Annu Rev Immunol.
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Zamvil SS, Steinman L. Expression of rat cathepsin S in phagocytic cells. Select Photo s.
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Ii p and pexpressing mice developed EAE with similar incidence to and HPLC purified by QCB Inc. (Hopkinton, Massachusetts, USA). GSA Pricelist P3I, Incorporated (P3I, Inc.) Hopkinton, MA in this contract are available at the following website address (URL):
You must select an email preference. In this regard, it was reported that APCs from mice deficient in Cat S have defects in Ag processing and were less susceptible to collagen-induced arthritis, an autoimmune disease mediated by pathogenic Th1 cells Remove Flower. Benjamin Bixby — Mice were perfused with PBS during euthanasia to remove circulating blood cells.
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The proteolytic environment involved in MHC class II-restricted antigen presentation can be modulated by the p41 form of invariant chain.
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